
The Majority of Patients Treated With EYLEA Had a Dry Retina at Year 1
Patients with a dry retina at Year 1 (post hoc analysis)2,5




The analyses of these post hoc endpoints were not multiplicity protected and are descriptive only.
Anatomic measures did not
influence treatment decisions in
Year 1 but were considered in Year 2.3
OCT, optical coherence tomography; Q4, every 4 weeks; Q8, every 8 weeks.
61% to 62% of Patients Had a Dry Retina With Q12 Dosing at Year 2
Integrated VIEW 1 and VIEW 2 (post hoc subgroup analysis)
Patients with a dry retina at Year 2 who had received only Q12 dosing after Year 16,*



The analyses of these post hoc endpoints were not multiplicity protected and are descriptive only.
Anatomic measures did not influence treatment decisions in Year 1 but were considered in Year 2.3
OCT, optical coherence tomography; Q4, every 4 weeks; Q8, every 8 weeks; Q12, every 12 weeks.
Sustained Central Retinal Thickness Reduction Data
EYLEA decreased mean central retinal thickness by ≈130 μm to 150 μm regardless of dosing schedule across VIEW 1 and VIEW 2.4
Integrated VIEW 1 and VIEW 2 (prespecified exploratory analysis)
Mean change in CRT through Year 2 from baseline2,4,*


The analyses of these exploratory endpoints were not multiplicity protected and are descriptive only.
Anatomic measures did not influence treatment decisions in Year 1 but were considered in Year 2.3
CRT, central retinal thickness; OCT, optical coherence tomography; Q4, every 4 weeks; Q8, every 8 weeks; Q12, every 12 weeks.
EYLEA Q12—Mean Reductions in CRT With Less Frequent Dosing in Year 2
Integrated VIEW 1 and VIEW 2 (post hoc subgroup analysis)
Mean reduction in CRT through Year 2 from baseline in eyes treated only with Q12 dosing after Year 16,*


The analyses of these post hoc endpoints were not multiplicity protected and are descriptive only.
Anatomic measures did not influence treatment decisions in Year 1 but were considered in Year 2.3
CRT, central retinal thickness; Q4, every 4 weeks; Q8, every 8 weeks; Q12, every 12 weeks.

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