Demonstrated Safety Profile in MEfRVO

The most common adverse reactions (5%) reported in patients receiving EYLEA were conjunctival hemorrhage, eye pain,
cataract, vitreous detachment, vitreous floaters, and intraocular pressure increased.1

VIBRANT, COPERNICUS, and GALILEO:
Most common adverse reactions (≥1%)1

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Most common adverse reactions in patients with MEfBRVO and MEfCRVO  receiving EYLEA®, Chart
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Most common adverse reactions in patients with MEfBRVO and MEfCRVO  receiving EYLEA®, Chart
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Most common adverse reactions in patients with MEfBRVO and MEfCRVO  receiving EYLEA®, Chart
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Most common adverse reactions in patients with MEfBRVO and MEfCRVO  receiving EYLEA®, Chart

Most common adverse reactions in patients with MEfBRVO and MEfCRVO  receiving EYLEA®, Chart

Less common adverse reactions reported in <1% of the patients treated with EYLEA in the
CRVO studies were corneal edema, retinal tear, hypersensitivity, and endophthalmitis.1

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Reference
  1. EYLEA® (aflibercept) Injection full U.S. Prescribing Information. Regeneron Pharmaceuticals, Inc. March 2021